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or Child-Pugh class A by 71.78% and 29.17% (p less then 0.05); class B - by 100.16% and 58.93% (p less then 0.05); class C - by 144.30% and 86.24% (p less then 0.05). It is also evidenced by the increasing D-dimers.; The increase in tPA, PAI-1, D-dimers and decrease in the tPA/PAI-1 index can predict the risk of thrombogenic state in patients with ALC, especially with concomitant adiposity.The goal of research is to optimize the results of surgical treatment of the regional metastases of the maxillofacial area cancer by improving the t