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To investigate the significance of ultrasound elastography for evaluating stiffness of the human lens nucleus in volunteers with different ages. A total of 90 volunteers (lens transparency, uncorrected visual acuity ≥0.5, intraocular pressure 14-19 mm Hg) were divided into 3 groups according to age Group A (30 people, median age 82±3.5y, mean axial lengths 23.7±0.5 mm); Group B (30 people, median age 46±2.1y, mean axial lengths 23.9±0.4 mm); and Group C (30 people, median age 22±3.5y, mean axial lengths 24.0±0.4 mm). Lens nuclear stiffnes