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9%, 6.7%, and 4.3% per year, respectively. Multinomial logistic regression analyses revealed that the correlation between the decline in estimated daily smoking rates and decline in detection rate of UIAs (hazard ratio 52.5 CI = (14.9,∞), p 0.00001) and incidence of SAH (hazard ratio 11.8 CI=(5.6,32.5), p 0.00001) are statistically significant. The association is particularly strong in young and middle-aged cohorts ( 66 years old). It is likely that reducing cigarette smoking on a population-based level strongly reduces the rates of UIAs and S