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CONCLUSIONS Transfemoral transcatheter puncture of IVS is feasible and safe in a swine design, and enormous sheath can be introduced into LV transfemoral-venously with the novel access utilizing the aid of vessel circuit. © 2020 Wiley Periodicals, Inc.Hematological conditions, including leukemia, lymphoma and multiple myeoloma, are described as high heterogeneity with diverse cellular subpopulations. Single-cell RNA sequencing (scRNA-seq), a transf