https://www.selleckchem.com/pr....oducts/lonidamine.ht
However, this transactivation was inhibited by inducing PAR2 degradation following PLAG treatment and metastatic activity was effectively inhibited. PLAG attenuated cancer metastatic activity via modulated PAR2/EGFR transactivation by accelerating PAR2 degradation. These results suggest PLAG as potential therapeutic agent to combat tumor metastasis via regulating the activation signal pathway of PAR2 by tumor infiltrate-neutrophils.Keywords Fiji; working horse; welfare, intervention; husbandry; healthcare.Atherosclerosis is the leadi