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All the responders had a significant improvement in their overall QoL after both types of treatment. Both BTX and SNM, in our experience, were safe and effective in managing our patients with refractory OAB after 6months of follow-up, which was also reflected by an improvement in their QoL. BTX botulinum toxin A; IPG implantable pulse generator; OAB overactive bladder; PVR post-void residual urine; QoL quality of life; SNM sacral neuromodulation; UDS, urodynamics; UI, urinary incontinence. BTX botulinum toxin A; IPG implantable pulse gen