https://adiporonagonist.com/ph....renic-neurological-a
Although many RNAs contain sequences that fold into RNA G4s (rG4s) in vitro, their folding and features in vivo aren't well comprehended. In this report, we indicated that the folding of putative rG4s in individual cells into rG4 structures is dynamically regulated under tension. By making use of high-throughput dimethylsulfate (DMS) probing, we identified hundreds of endogenous stress-induced rG4s, and validated all of them using an rG4 pull-down method. Our outcomes display that stress-in
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