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1). During follow-up, 117 patients (11%) developed at least one ischemic event. The incidence rate of total ischemic events increased with increasing LA size. Severe LAE was independently associated with increased risk of ischemic events compared with normal LA size (multivariable-adjusted hazard ratio, 1.75; 95% confidence interval, 1.02-3.0. Severe LAE was associated with increased risk of ischemic events after ischemic stroke or TIA in patients with NVAF. Severe LAE was associated with increased risk of ischemic events after ischemic
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