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Summary Understanding the spectrum of neurological manifestations of COVID-19 and the impact of COVID-19 on patients with underlying neurological conditions might help to improve outcomes.Background Recent studies have reported observing antioxidant, anti-inflammatory, and anti-aging properties of α-L-Guluronic acid (G2013) in animal and human studies. It has been theorized that the antioxidant and anti-inflammatory properties of G2013 might be beneficial in epilepsy treatment. Objective We sought to determine G2013's effects on epileptic