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Participants are followed up at 1.5 and 3 years old for home visits, and 2, 4, 6 and 8 years old for developmental/medical examination. The details of protocols after age 10 are under discussion. Of 10,302 selected children, 5,017 participated. The profiles of the participating mothers, fathers and children did not substantially differ between the Main Study and Sub-Cohort Study. The JECS Sub-Cohort Study offers a platform for investigating associations between environmental exposure and outcomes. The JECS Sub-Cohort Study offers a platf