https://www.selleckchem.com/pr....oducts/SB-203580.htm
Germline genetic variants of human telomerase reverse transcriptase (hTERT) are known to predispose for various malignancies, including glioma. The present study investigated genetic variation of hTERT T/G (rs273610 and hTERT G/A (rs2736098) with respect to glioma risk. Confirmed cases (n = 106) were tested against 210 cancer-free healthy controls by the polymerase chain reaction-restriction fragment length polymorphism technique for genotyping. Homozygous variant 'GG' genotype of rs2736100 frequency was 4-fold significantly di