https://www.selleckchem.com/pr....oducts/crenolanib-cp
To evaluate outcomes and postoperative toxicities after intraoperative radiotherapy (IORT) in elderly women. Women older than 65 years, with infiltrating ductal breast cancer ≤3 cm, expressing estrogen receptor (ER+) without Her2 overexpression, and with negative axillary nodes. Treatment consisted of partial mastectomy with a sentinel lymph node biopsy (SLN procedure; in case of positive SLNB, IORT was cancelled. IORT consisted in a total dose of 20 Gy in 1 fraction delivered at the surface of the applicator with the Int