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Results Fifty-eight associated with the 375 pSS patients (15.5%) were seronegative for ANA, RF, anti-Ro, and anti-La autoantibodies. Seronegative pSS had been identified according to lymphocytic infiltrations in lip biopsy samples. There have been no statistically considerable differences in regards to diligent age, age at analysis, intercourse distribution, medical functions, and laboratory results between seronegative and seropositive pSS. The regularity of hypergammaglobulinemia ended up being