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The change in CMT at 3 months was statistically but not clinically significant in the treatment-naïve group only (mean ± SD; -30 ± 130 µm; = 0.011). The macular volume and area thickness change were not statistically significant ( = 0.173 and = 0.148 for macular volume and area thickness, respectively) in the treatment-naïve group. There was no difference concerning the leakage area in both groups. No adverse events were reported. We concluded that micropulse 577nm laser therapy maintained the visual acuity and macular thickness at 3 months in bo