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There has been substantial interest on the effect of large-scale environmental change, such as deforestation, on human health. An important and relatively recent development has been the use of causal-inference approaches (e.g., instrumental variables [IVs]) to more properly analyze this type of observational data. Here, we discuss an important study that attempted to disentangle the effect of malaria on deforestation from the effect of deforestation on malaria using an IV approach. The authors found that deforestation increases malaria
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