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4. Heterogeneity was moderate to high (I = 61; 95% CI= 28-79), and there was significant risk of publication bias (p .04). The 2 studies in children less than 12 years of age showed nonsignificant effects (g= 0.01; 95% CI= -1.16 to 1.18). We found no significant effect on the incidence of major depression at follow-up (relative risk= 0.52; 95% CI= 0.25-1.08), although this may be related to low statistical power. Interventions for subthreshold depression may have positive acute effects in adolescents. There is currently insufficient ev