https://www.selleckchem.com/pr....oducts/pf-03084014-p
In contrast, heroin and cocaine co-use (AOR=1.062 (1.027, 1.099)) and heroin use (without cocaine) (AOR=1.101 (1.070, 1.133)) linearly increased from 2002 to 2017. Screening, outreach, clinical treatment, and first responders should be aware of increasing patterns of polysubstance use and the potential implications of co-use of heroin and cocaine on first responders' intervention and the potential role of increasing exposure to multiple substances on overdose outcomes in the US. Screening, outreach, clinical treatment, an