https://www.selleckchem.com/pr....oducts/sorafenib.htm
Cardiopulmonary parameters were measured during an incremental cycle exercise test. RESULTS BR caused 10-15% loss of PF volume that was partly recovered 3 days after re-ambulation, as a consequence of fluid redistribution. Unexpectedly, PF fatigue resistance was not affected by BR or NUTR. BR induced a shift in muscle metabolism toward glycolysis and some signs of impaired muscle oxygen extraction. NUTR did not attenuate the BR-induced-shift in energy metabolism. CONCLUSIONS Twenty-one days' BR did not impair PF fatigue resistance, bu
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