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ADHD Medications and Treatments The primary drugs used to treat ADHD are stimulants. They boost neurotransmitters, which help control impulses and improve concentration. Adderall and dextroamphetamine are two examples, along with methylphenidate and lisdexamfetamine. Ritalin, also known by their brand names. If stimulants are not effective or cause too many adverse side adverse effects, doctors might prescribe antidepressants, such as Wellbutrin. These medications target dopamine and norepinephrine, which are the bra