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How Does Medication For ADHD Work? Many people find that taking medication improves their symptoms. Finding the right medication in the right dosage takes time, communication open and a willingness to listen to your GP. Treatments for ADHD are able to alter the levels of certain chemical messengers within your brain. Stimulant medicines, like methylphenidate, help focus and reduce impulsivity and hyperactivity. Atomoxetine and guanfacine, both non-stimulant medications that improve behaviou