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19 higher chances of presenting altered CRP levels (values ≥3mg/L- T2 to T3) than those without periodontitis recurrence (95%CI1.16-3.27; p=0.017). Higher CRP plasma levels were associated with higher recurrence of periodontitis and worse clinical periodontal parameters among IC when compared to RC. Higher CRP plasma levels were associated with higher recurrence of periodontitis and worse clinical periodontal parameters among IC when compared to RC. Diabetes prevalence within the global population has nearly doubled since 1980, with the