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Water pollution caused by heavy metal leaves human beings exposed to various health risks. Although many studies have focused on the efficiency of industrial water use (IWU) systems, few studies further address analysis for the harmful effect of heavy metal polluted water on human health. This paper first considers both IWU and healthcare (HC) systems as an integrated two-stage IWUHC system. Detailed efficiencies and its dynamic evolution are further revealed by integrating a dynamic two-stage DEA model within a slacks-based measure a