https://www.selleckchem.com/pr....oducts/Cyclopamine.h
Indole-3-carbinol (I3C) is a natural compound derived from brassica vegetables, displaying antibacterial activity. The study aims to elucidate the antibacterial mode of action(s) induced by indole-3-carbionol in Escherichia coli and enhance the understandings on the respective contribution of each reactive oxygen species (ROS), superoxide anion (O ), hydrogen peroxide (H O ), hydroxyl radical (OH ) during the process. The antibacterial activity of I3C was assessed through kinetic assay. The generation of ROS was measured by flow cyt