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d time-consuming processing in the central nervous system. We used deconvolution analysis with MB EPI and tent functions to identify the delayed increase in the BOLD signal in the area related to pain perception specifically observed in real acupuncture stimulation. We propose that the specific BOLD signal change observed in this study will lead to the elucidation of the mechanism underlying the therapeutic effect of acupuncture stimulation. The cardiac- and respiratory-driven components of cerebrospinal fluid (CSF) motion characterist