https://www.selleckchem.com/pr....oducts/alkbh5-inhibi
We identified 1840 (32.7%) patients with intact primaries and 3784 (67.3%) patients with prior resection. The cumulative incidence of nonelective surgery 1year after initiating bevacizumab for all patients was 3.9% (95% CI 3.4-4.5%). One-year cumulative incidence was higher in those with intact primaries than in those with resected primaries (6.1% vs 2.9%, P0.0001). After adjustment, an intact primary remained strongly associated with nonelective colorectal surgery (hazard ratio=2.89, 95% CI 2.32-3.61; P0.0