https://www.selleckchem.com/pr....oducts/Etopophos.htm
PURPOSE To determine the role of NLRP3 inflammasome activation in low-dose radiation-induced radiation pneumonitis (RP) and to assess whether the inhibition or deletion of the NLRP3 inflammasome is critical for conferring protection against RP. MATERIALS AND METHODS THP-1 cells were treated with increasing doses of radiation to assess the activation of NLRP3 by Western blot and ELISA. Reactive oxygen species (ROS) production was measured by flow cytometry, with or without ROS inhibitor treatment. A mouse thoracic radiation model that
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