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The test was terminated early with 44 (22 per arm) of this planned 66 patients as a result of slow accrual. Customers' qualities had been really balanced with median baseline creatinine clearance of 98.0 and 95.1mL/min within the furosemide and mannitol arms, correspondingly. In the 1st cycle, two (9%) and four (18%) patients created level 1 creatinine height (P=.66), correspondingly, despite no ≥ grade 2 toxicity. The median times to produce the worst creatinine rating had been 10 and