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The current findings can improve the understanding of the structural evolution behavior of PCL/RGO nanocomposites after shear and especially enhance dramatically our understanding of the underlying mechanism of influence of shear on interfacial epitaxial crystallization in polymer/graphene nanocomposite systems.Based on the targeting of ferroferric oxide (Fe3O4) and the drug-loading property of carbon nanotubes (CNTs), a novel Span-PEG-composited Fe3O4-CNTs-DOX multifunctional ultrasound contrast agent was designed and applied to tumor le