https://www.selleckchem.com/pr....oducts/sb-415286.htm
BACKGROUND Recent studies have shown that amyloid-β (Aβ) burden influenced white matter (WM) integrity before the onset of dementia. OBJECTIVE To assess whether the effects of Aβ burden on WM integrity in cognitively normal (CN) individuals were regionally specific. METHODS Our cohort consisted of 71 CNs from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database who underwent both AV45 amyloid-PET and diffusion tensor imaging. Standardized uptake value ratio (SUVR) was computed across four bilateral regions of interest (ROIs
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