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Moreover, we discovered overexpression of miR-27a reversed the antiproliferation and pro-apoptotic effects of APS on OC cells. F-box and WD-40 domain protein 7 (FBXW7), a classical tumefaction suppressor, ended up being discovered directly focused by miR-27a and its interpretation had been stifled by miR-27a in OC cells. Finally, it absolutely was additionally observed that knockdown of FBXW7 by si-FBXW7 reversed the tumor suppressive task of APS in OC cells, which will be much like the effe
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