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Finding the Best ADHD Medication For Adults Many adult ADHD treatment plans are based on medication. Finding the right medication dosage and dose isn't always easy. Stimulants: These medicines are used to treat hyperactivity and inattention. They work by increasing the levels of chemicals that transmit messages between nerve cell. They are administered several times a day and begin working in less than an hour. Stimulants Most doctors begin with stimulants to treat ADHD. The