https://cpi-169inhibitor.com/d....evelopment-associate
This review suggests that just those molecules have actually high rate constants when you look at the 107-109 mol-1 dm3 s-1 range which have special electron rich part(s). These molecules tend to be eliminated selectively in CO3- reactions. Such electron wealthy moiety could be the NH2 team attached to an aromatic band. Tall vales were measured e.g., for some of anilines or the sulfonamide antibiotics. -CO team connected to the N-atom (in acetanilides and in phenylurea
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