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Leptus (Leptus) grancanaricus n. sp. and L. (L.) machadoi n. sp. are described from Gran Canaria and Fuerteventura (Canary Islands). They were collected from new hosts for the genus Leptus Herpisticus guanarteme Machado and Laparocerus maxorata Machado (Coleoptera Curculionidae). New metrical data for Leptus (Leptus) andae, L. (L.) akkus, L. (L.) hammameticus, L. (L.) horiacus and L. (L.) tammuzi based on examination on the type-material are provided.Apoptosis/cell death and reactive oxygen species (ROS) via overload free Ca2+ and Zn2
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