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These layers have been demonstrated to have unique structure and morphology, also to play a role in corneal homeostasis and clarity, take part in the control of corneal hydration and also to modulate TGF-β-induced posterior corneal fibrosis. Pathophysiological modifications of Descemet's membrane layer tend to be mentioned in ocular conditions such as Fuchs' dystrophy, bullous keratopathy, keratoconus, main congenital glaucoma (Haab's striae), as well as in systemic problems. Unrepaired
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