https://www.selleckchem.com/pr....oducts/bay-11-7082-b
rchers to select culture media that ensure consistent mAB sialylation. The skeletal muscle Cl channels, the ClC-1 channels, stabilize the resting membrane potential and dampen muscle fibre excitability. This study explored whether ClC-1 inhibition can recover nerve-stimulated force in isolated muscle under conditions of compromised neuromuscular transmission akin to disorders of myasthenia gravis and Lambert-Eaton syndrome. Nerve-muscle preparations were isolated from rats. Preparations were exposed to pre-or post-synapt