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In inclusion, the high expression of HDGF ended up being reported to be closely related to undesirable medical effects in lot of cancerous diseases. Thus, HDGF is considered to play a role in the growth and progression of malignant disease. We herein provide a short history associated with the aspect as well as its features with regards to harmless and malignant cells. We also explain its likely role as a target molecule for digestive malignancies.The discovery of antibiotics