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001), and deep tissue injury/wounds (OR 1.9, 95% CI 1.4-2.6, p less then 0.001). Head trauma with intracerebral bleeding was only weakly associated (OR 2.0, 95% CI 1.2-3.5, p = 0.01) and head trauma without intracranial bleeding was not associated with an increased S-100 B protein level (p = 0.71). Trauma severity was also related to increased S-100 B levels (OR per ISS 1.1, 95% CI 1.0-1.1, p less then 0.001). S-100 B levels less then 0.57 µg/L had a high diagnostic value to rule out in-hospital mortality (negative predictive value 1.0,
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