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leukodystrophies and other pediatric neurologic diseases offers a method for targeting improved care for patients by identification of morbidities. Nationwide data on patients with cryptogenic stroke (CS) are lacking. We evaluated patient and hospital characteristics, in-hospital treatments, and discharge outcomes among patients with CS compared with other subtypes in the Get With The Guidelines (GWTG)-Stroke registry. We identified patients with ischemic stroke (IS) admitted to GWTG-Stroke participating hospitals between January 1, 2016,