https://www.selleckchem.com/pr....oducts/PF-2341066.ht
Miltefosine is an alkylphosphocholine drug with proven effectiveness against various types of parasites and cancer cells. Miltefosine is not only able to induce direct parasite killing but also modulates host immunity, for example by reducing the severity of allergies in patients. To date, there are no reports on the effect of miltefosine on eosinophils, central effector cells involved in allergic inflammation. We tested the effect of miltefosine on the activation of human eosinophils and their effector responses in vitro and in mous