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The phytoestrogen genistein could possibly be a secure preventive method. The first purpose of this work was to validate a model of cardiac breathtaking in which natural estrogenic deficiency rats, for example adult young male (YM) and aged female (AgF), are compared to youthful feminine rats (YF). The 2nd aim was to study whether or not the in vivo administration of genistein prevents the wonderful in estrogenic deficiency rats. The next aim