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3% and 52.6% of patients, respectively. IOP at one week post-op was a predictor of success, and the needling rate was inversely correlated to early post-op IOP. The number of pre-operative medications and patientage were not significantly associated with failure. CONCLUSIONS Insertion of the XEN 45 stent alone or combined with phacoemulsification is effective and safe in the treatment of open angle glaucoma, with a substantial reduction in IOP and number of medications. Future randomized, comparative studies on the use of this device are w