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ADHD Stimulant Medication About 70 to 80percent of children and adults with ADHD benefit from stimulants. They alleviate symptoms by boosting dopamine and norepinephrine levels. These medicines begin working within 30 to 45 minutes, and last for 3 to 6 hours. These medicines are available in chewable or liquid tablet in tablet form. Nonstimulant medications can be prescribed by your physician to supplement stimulants. These include the drugs atomoxetine (Strattera) and Guanfa