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Medication For ADHD - What Are the Side Effects? Many people suffering from ADHD experience a reduction in symptoms when they use medication. But every person reacts differently to various drugs, and adverse reactions can be problematic. Methylphenidate is a stimulant. It is a stimulant that increases levels of a brain chemical that regulates behavior and attention. improve attention and concentration for 70% to 80% children and adults who take it. They affect the