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Adult ADHD and Comorbid Disorders Many adults suffering from ADHD also suffer from comorbid disorders like major depressive disorder (Kessler and colleagues, 2006). Many sufferers do not respond to medications for depression and may be able to benefit from psychotherapy. Neurotransmitters are brain chemicals that regulate and increase levels of certain brain chemicals. Stimulants such as methylphenidate and amphetamine are often prescribed. Medications Adults are able to take many different drugs that ar