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ADHD Medications For Adults Stimulants can help regulate the levels of chemical messengers that regulate the brain's attention. They are considered to be the first line of treatment for ADHD. While they do not cause in any way habit-forming, they can trigger adverse effects like headaches and difficulty sleeping. To reduce hyperactivity or impulsivity, your doctor may prescribe guanfacine with the brand names Tenex or Intuniv (Catapres). These drugs have a longer duration of action than stimulants. are among the drugs that are most commonly prescribed to treat AD