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There is a down-regulation associated with the pro-neuronal genes, ngn1 and atoh1b in the context of gfi1.2 knockdown, that has been rescued by the exogenous gfi1.2. We also found that gfi1.2 may regulate ngn1 phrase by curbing id2a. Our outcomes recommended that knockdown of gfi1.2 may induce deafness through promoting cells proliferation in the pro-sensory area and interrupting cell differentiation.Heat treatment, or thermal disinfection, is among the most b