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633; P = 0.015), and remote progression (HR 2.016; P = 0.003). Symptomatic adverse radiation effects occurred in 1 patient. Salvage GKS and cranial surgery were performed in 9 (24.3%) and 8 (21.6%) patients, respectively. Progression to WHO grade 2-3 occurred in 5 (13.5%) patients. A larger preoperative maximum diameter was a risk factor for progression of WHO grade (HR 2.016, P = 0.033). Progression out of the margin dose was associated with a larger preoperative tumor size. AIM Based on our clinical observations, low emotional intelligence level and probl