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These results support previously proposed immune mechanisms triggering the AGS and provided evidence for new mechanisms also potentially involved in the AGS. These results support the use of the zebrafish animal model for the study of the AGS and other tick-borne allergies. Copyright © 2020 Contreras, Pacheco, Alberdi, Díaz-Sánchez, Artigas-Jerónimo, Mateos-Hernández, Villar, Cabezas-Cruz and de la Fuente.Lipids are essential players in parasites pathogenesis. In particular, the highly phagocytic trophozoites of Entamoeba histolytica, th