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0521 / 0.8337). In calf muscles mDTI showed significant differences between DM 1 and DM 2 patients (all p 0.0001) as well as between DM 1 patients and controls (all p = 0.0001). Thigh muscles had a significant higher fat-fraction in both groups vs. controls (p 0.05). There was no correlation of CTG triplet length with mDTI values and fat-fraction. mDTI reveals specific changes of the diffusion parameters and fat-fraction in muscles of DM 1 and DM 2 patients. Thus, the quantitative MRI methods presented in this study provide a powe
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