https://www.selleckchem.com/pr....oducts/NVP-AUY922.ht
Dysregulation of dopaminergic neurotransmission, specifically altered reward processing assessed via the reward anticipation in the MID task, plays a central role in the etiopathogenesis of neuropsychiatric disorders. We hypothesized to find a difference in the activity level of the reward system (measured by the proxy reward anticipation) under drug administration versus placebo, in that amisulpride reduces, and L-DOPA enhances, its activity. We studied the influence of dopamine agonist L-DOPA and the antagonist amisulpride on the r